Static Magnetic Field Modulates Rhythmic Activities of A Cluster of

23 With the development of superconducting magnets, the chances of exposure to 24 intense static magnetic fields (SMFs) have increased. Therefore, safety concerns related 25 to magnetic field exposure need to be studied, especially the effects of magnetic field 26 exposure on the central nervous system. Only a limited number of studies prove a direct 27 connection between magnetic fields and electrophysiological signal processing. Here we 28 described a cluster of large local interneurons (LNs) located laterally to each antennal 29 lobe of Drosophila melanogaster, which exhibit extensive arborizations throughout the 30 whole antennal lobe. Dual recordings showed that these large LNs demonstrated 31 rhythmic spontaneous activities that correlated with other LNs and projection neurons 32 (PNs) in the olfactory circuit. The results suggest that 3.0 Teslas SMF can interfere with 33 the properties of the action potential, rhythmic spontaneous activities of large LNs and 34 correlated activity in pairs of ipsilateral large LN/LN in the olfactory circuit. This 35 indicates that Drosophila can be an ideal intact neural circuit model and the activities of 36 the olfactory circuit can be used to evaluate the effects of magnetic field stimulations. 37 38